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  Home::Overviews of the Zebrafish Model and Fish Neoplasms
  Overviews of the Zebrafish Model and Fish Neoplasms

Zebrafish (Danio rerio) is very popular freshwater tropical fish, which has emerged as a major model organism for biomedical research, especially in developmental genetics, neurophysiology, oncology and biomedicine. In fact, the zebrafish has been recognized as a promising animal model for cancer research. Compared to mammals, the induction of cancer in fish appears to be easy. At the same time, the zebrafish has been found to be a responsive, cost-effective lower vertebrate model system to study the mechanism of carcinogenesis Liver has been found to be the most commonly targeted organ in the cancer studies with zebrafish. The neoplasms which have been reported in zebrafish include: seminoma, hepatocellular carcinoma (HCC), hepatocellular adenoma (HCA), adenoma of exocrine pancreas, intestinal adenocarcinoma, ultimobranchial neoplasm, thyroid neoplasm, spindle cell sarcoma and hemangioma, etc. In the present article, therefore, overviews of the zebrafish model and the neoplasms occurring in zebrafish have been elucidated.

Date: 15, Sep 2012 Posted By: admin
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