Search Journals
 
Wednesday, September 22, 11:45:00 AM
 
  Home::Spectrophotometric Method Development and Validation for Simultaneous Estimation of Rosuvastatin Cal
  Spectrophotometric Method Development and Validation for Simultaneous Estimation of Rosuvastatin Cal
   

Few UV spectrophptometric and chromatographic methods were reported in the literature for the estimation of Rosuvastatin calcium and Telmisartan. The objective of the study is to develop and validate analytical methods for simultaneous estimation of these drugs in bulk and combined dosage form. Therefore, Sensitive, rapid and specific spectrophotometric methods have been developed. In the Simultaneous Equation Method, wavelengths selected for Rosuvastatin Calcium and Telmisartan were 242.0nm and 295.5nm respectively in 0.1N Sodium Hydroxide solution. In Absorbance Ratio Method, wavelengths selected were 286.0nm (isoabsorptive point) and 242.0nm in the same solvent. Linearity range was observed in the concentration range of 8-20g/ml for Rosuvastatin Calcium and 2-10μg/ml for Telmisartan. The developed methods are simple, rapid, accurate, precise, reproducible and economic and can be used for routine quantitative analysis of Rosuvastatin Calcium and Telmisartan in pure and tablet dosage form and validated using ICH Guidelines

Date: 15, Sep 2012 Posted By: admin
   
 
  Login Here
  User Name
 
  Password
 
  Remember Me
  Create an Account
Forgot your login or password?
   
Home | Aim & Scope | Editorial Board | Instructions to Authors | Download | Online Submission | . | Invitation Letter | . |  
Total Visits:
Free website hit counter
Copyright © TGJ. Powered by Web Power India.