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  Home::Formulation and Evaluation of Ophthalmic Dosage form containing anti-Inflammatory Drug
  Formulation and Evaluation of Ophthalmic Dosage form containing anti-Inflammatory Drug
   

The objective of the present investigation is to prepare, characterize and evaluate the emulsion eye drop of anti-inflammatory, the eye drops were prepared by stirring method by using over head homogenizer. The excipients were used for their compatibility with steroidal anti-inflammatory, there was no chemical and physical interaction occurred. The pre-formulation parameter such as API characterization, selection of excipients and selection of order of addition of excipients were studied. The description, osmolality, pH, viscosity, assay, preservative, content and relative substance were evaluated for ophthalmic emulsion. The effect of these variables on the drug release profile of steroidal anti-inflammatory was also studied. The emulsion eye drop were formulated using 5.5 pH phosphate buffer of sorbic acid as preservative and Glycerine for adjusting the osmolarity. The result indicated that the selected formulation was stable during the test period of accelerated stability studies. All the evaluated result was found to be satisfied.

Date: 29, Sep 2012 Posted By: admin
   
 
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