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  Home::MADHUCA INDICA: REVIEW ON HEPATOPROTECTIVE MECHANISMS AND OTHER MEDICINAL USES
  MADHUCA INDICA: REVIEW ON HEPATOPROTECTIVE MECHANISMS AND OTHER MEDICINAL USES
   

Hepatotoxicity is one of the major health issues in India now a days, it is complex in nature and can be occur by single or combination of several disease together. There are synthetic medicines for the prevention of hepatotoxicity but are not as satisfactory and safe as the natural and traditional medicine. Madhuca indica that is also known as mahua tree in India belongs to Sapotaceae family has potency against hepatotoxicity. The mechanism of action of Madhuca indica is a result of combination of other protective activity like Anti diabetic, antiulcer, hepato protective, anti pyretic, anti fertility, analgesic, anti oxidant, swelling, inflammation, piles, emetic, dermatological, laxative, tonic, anti burn, wound healing. It is also used in treatment of headache, piles, and as an anti earth worm. The main cause of liver disease is oxidation of cell component and thus generation of free radicals, other mechanism are also involved in the liver damage like irregularity in the cell membrane permeability and lack of synthesis of protein through ribosomal RNA. Madhuca indica have the flavonoids and other main active constituents that act as an anti oxidant and prevent the oxidation of cell component in human body. It prevents the liver damage by any of mechanism either by controlling cell membrane permeability or by accelerating the protein synthesis. Although it has therapeutic activity it also has some toxic constituent like aflatoxine in Madhuca indica seed oil.

Date: 12, Mar 2013 Posted By: admin
   
 
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