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  Home::A REVIEW ON GASTRO-RETENTIVE DRUG DELIVERY WITH SPECIAL EMPHASIS ON FLOATING DRUG DELIVERY SYSTEM
  A REVIEW ON GASTRO-RETENTIVE DRUG DELIVERY WITH SPECIAL EMPHASIS ON FLOATING DRUG DELIVERY SYSTEM
   

The modern scientific and technological advancements in the pharmaceutical field had created bank of interest in novel dosage form in the recent years. A variety of technical and scientific approaches is been conducted in the field of research and development for the formulation of an efficacious rate controlled release of oral drug delivery system. The basic aim behind developing this novel drug delivery system was to overcome the physiological diversities such, as short span of gastric residence time, unpredictable gastric emptying time which leads to lesser absorption and decreased bioavailability. The purpose of writing this review on floating drug delivery system was to collect all the recent updates from the literature with the main goal to emphasize on the principle of mechanism of floating that basically deals with the prolongation of gastric emptying rate and there by improves the bio-availability of typical drugs which are sensitive towards gastric fluid. This review also summarizes, regarding the techniques towards the achievement of floating state, its formulation aspects, polymers incorporated, and drugs compatible in these process, merits and demerits, its evaluation parameters, along with its application in the clinical world.

Date: 13, Dec 2012 Posted By: admin
   
 
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