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  Home::Experimental diabetes using a new model of induction: Histological and Stereological evaluation of t
  Experimental diabetes using a new model of induction: Histological and Stereological evaluation of t

Interpreting histological sections with three dimensional principles helps to solve some of the essential issues with qualitative microscopy as regards to spermatogenic process. Oxidative stress as a result of hyperglyceamia has been linked with testicular failure leading to sexual dysfunction, impotence and infertility. The effect of extract from bay leaf on the testes of diabetic rats was investigated. Twenty-one adult male Sprague–Dawely rats (250–300g) were divided into three groups containing 7 animals each. The first group served as control and was gven1.5 ml/kg b. wt. distilled water as vehicle. The second and third group was treated with a single dose of alloxan (40 mg/kg b. wt.) through their penial vein. The third group in addition received 60 mg/ kg b. wt. aqueous extract of bay leaf every day for four weeks. Results showed a significant reduction in the mean seminiferous tubular diameters (97.2±1.2 μm), cross-sectional area (17.31±4.0), number of tubular profiles per unit area (15.14±0.2) and the mean numerical tubular density (7.11±8.0) of the diabetic untreated rats. There was an improvement in testicular geometry of the diabetic group of rat treated with bay leaf extract. Laurus nobilis extract improved the diabetic-testis of rat. This was evident by the histo-morphometrical evaluation in our study.

Date: 08, Apr 2013 Posted By: admin
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