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  Home::Evaluation of Phytochemical Screening and Antinociceptive Properties of the Ethanolic Extract of Vit
  Evaluation of Phytochemical Screening and Antinociceptive Properties of the Ethanolic Extract of Vit
   

The antinociceptive activity was evaluated in acetic acid induced writhing model in mice. Phytochemical screening of the leaf extract of Vitis setosa (family: Vitaceae) grown in Bangladesh had indicated the presence of reducing sugars, alkaloids, tannins and saponins. At the dose of 250 mg/kg and 500 mg/kg body weight, the extract showed a significant antinociceptive activity showing 23.75% and 36.25% inhibition respectively (P<0.001) comparable to that produced by Diclofenac Na (67.50%) used as standard drug. The present study tends to suggest the antinociceptive activity of the crude ethanolic extract of the leaves of Vitis setosa and justify its use in folkloric remedies.

Date: 15, Sep 2012 Posted By: admin
   
 
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